What setup do you think that would look better?

Hello all i decided to go with the skylon rubicon series speakers for my X1. I am undecided on what setup to go with.

Option 1:
Single 450 in the center with one 150 on each side of the 450's.

Option 2:
A set of 350's and in the future add lights in between the speakers

Option 3:
A set of 350's and in between the 350's is a set of 250's.

Option 4:
A set of 450's.

The 450's are 2 8" mid with a horn in the middle.
The 350's are 1 8" mid with a horn.
The 250's are 2 6.5"s with 2 little tweeters.
The 150's are 1 6.5" with 1 little tweeter.

Don't worry about the cost but i want the best sounding setup. Also is bad to mix horns with 6.5" speakers? Or would it make the sound more well rounded? Any comments would be appreciated!!!!