We've got a houseboat out of Fleming and we take a different route from the East Bay. Its a little more difficult to follow, but after going to Pedro for years, I'm convinced it's the best route.
580 East (follow 580 as 205 splits off through Tracy)
132 East (continue on this through Modesto)
Left on La Grange Rd. (J59)
Right on Bonds Flat
Left into Fleming Meadows