Nick,
Congrats on the new boat!! I would recommend the St. John's River near Astor, FL. Daytona Beach is only about 35 miles away. The St. John's is mostly uninhabited, which makes it a paradise for scenery & wildlife. You do, however, have to know where to go since there are several no wake zones.
Here is a link (that includes pics of the river) to a motel lots of wakeboarders use:
http://www.blairsjungleden.com/motel.htm If you decide to lodge in Daytona Beach, you can put in on the St. John's just West of Deland on SR44. That's only about 25 miles out.
(Message edited by wakekat15 on February 02, 2009)