I'm not any sort of expert so take this with a grain of salt. What I always heard about trailer tires was that they were designed to better handle what happens to a trailer - i.e. sitting in one spot for a long time, possibly in the sun, and getting hit with a lot of UV. Regular street tires will be more likely to get a flat spot when they sit for too long. That's the reasoning I have heard, bu I have no proof to back that up.
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