Finishing up my audio install this weekend and i want to make sure i dont have a chance of engine noise. Just have to run 25 feet of speaker wire over to my amp and run two sets of rca's 18ft each. Rca's with oviously be very far away from my power and ground wire's. Where do you suggest i run my speaker wire? Zip tied up with the rca's or zip tied with my power and ground? Or away from them both?

speaker wire is fine since its already amplified its harder for noise to penetrate. <BR> <BR>RCA is different. RCA is line level so it is amplified many times when it reaches the amp, so any small amount of noise will be amplified X amount of times as well.

So what route do you think would be best and safe

Noise is most likely to enter the RCA's on the signal side, then the speaker wires on the output side. If you have an option, I would just stay away from the power/ground and be on the safe side.

Electroparamagnetic effect

If it's easy to keep the RCA and Speaker wire awat from each other, then do it, but just make sure you keep them both away from the Power wire.